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The National Evolutionary Synthesis Center (NESCent) held an exciting meeting focused on investigating evolution of organisms in the built environment, and especially in homes. Three BioBE researchers were in attendance (Ashley Bateman, Gwynne Mhuireach, and James Meadow), and the list of participants included experts in microbial genomics, architecture, building science, ethics, ecology, human evolution, sociology, and invertebrate zoology.