What We Do


Given that humans in the developed world spend 90% of their lives in enclosed buildings, we need to learn more about the biology of the built environment.  Buildings are complex ecosystems that house trillions of diverse microorganisms interacting with each other, with humans, and with their environment. Recent advances in microbial genomics offer the potential to significantly advance our understanding of the built environment “microbiome” – the totality of microbial cells, their genetic elements, and their interactions indoors.  To realize this potential, the Biology and the Built Environment (BioBE) Center is engaging with industry partners, conducting original research, and training a new generation of innovators and practitioners at the architecture-biology interface.  The vision of this national research center, founded with support from the Alfred P. Sloan Foundation, is to develop a hypothesis-driven, evidence-based approach to better understand the microbiome of the built environment (MoBE). Our goal is use this knowledge to optimize the design and operation of buildings and public spaces to promote both human health and environmental sustainability.

Current expertise and research

The BioBE Center is based at the University of Oregon and led by:

Our interdisciplinary team has expertise in sustainability and energy use in buildings, ecological theory, microbiology, indoor air and surface sampling, molecular sample preparation, high-throughput sequencing, and bioinformatic and statistical analyses.  Building on this expertise, we are addressing fundamental questions about architectural practices and the built environment microbiome.  These questions include but are not limited to:  what dispersal vectors (e.g. ventilation versus human occupancy) significantly influence the built environment microbiome? What attributes of the built environment (e.g. building materials, light exposure, air source and path) shape microbial community composition indoors?  How do the drivers of microbial biodiversity in the indoor environment vary with climate, geography, and building operation practices?